TALON

TALON Registry

TALON was a national, multi-center registry for tracking outcomes following treatment with the SilverHawk® System. The registry provided both site-specific and aggregate data on the acute and long-term results of plaque excision in the femoral-popliteal and tibial-peroneal vessels. Clinical endpoints of the study were 6-month and 12-month target lesion revascularization rates and patency rates. In addition to tracking clinical results, the TALON registry was designed to correlate outcomes with histology findings and genomic profiles. Plaque excised from enrolled patients is preserved for analysis. The ability to link actual long-term clinical results with histological, genomic and proteomic information embedded in the plaque may help lead to the identification of restenotic and arterial disease markers.

With hundreds of patients already enrolled, TALON is the largest registry of its kind focused on peripheral arterial disease.

• Preliminary results presented at the TCT meeting in September 2004 indicated low acute complication rates and a 6-month target lesion revascularization rate of 11.1%.
  
• One-year outcomes data presented at the SVS meeting in June 2005 reported an 80% clinical patency rate for blockages treated with plaque excision.

To read more about the TALON data, click here.